![]() In sum, we are constantly seeking new methods to artificially boost activity in extinction neural circuits as potential therapeutics for addiction and posttraumatic stress disorder. In addition to these techniques, the lab also routinely uses immunohistochemistry and confocal microscopy to visualize and image the neurons we manipulate, as well as perform neuroanatomical tracing and Fos expression analyses (Fos = a biochemical marker for neuronal activation). Jamie Vu, the opposite of dja vu from the French, meaning never seen, the illusion that the familiar does not seem familiar. We are also using fiber photometry to record neuronal population activity using virally transduced calcium sensors (GCaMP, RCaMP) in vivo during behavioral tasks. Here are other providers that practice at the same doctors office: Jamie Vu. ![]() We use optogenetic and chemogenetic viral strategies to manipulate neuronal activity within defined neural pathways and cell types. Therefore, much of our work focuses on neuroanatomical inputs and outputs to/from this brain region. We have discovered the infralimbic prefrontal cortex is a key brain region responsible for the inhibition of both drug seeking and fear after extinction learning. Toward these ends, we use self-administration addiction models, as well as models of conditioned fear, in rats. We are especially interested in understanding how these circuits change when an animal learns to inhibit a previously learned behavior, through a process called extinction learning. The main goal of our research is to identify the neural circuits controlling learned behaviors, primarily those controlling drug seeking and fear. Both feelings, as people describe them, seem similar. Peters joined the UAB Department of Neurobiology in 2023. De-realization is a feeling that the world around one has suddenly changed in characterbecome less real. jamie Pearly Benson straighthoney Ryan Condrick James Reeno (SPAZZOID.
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